The present study is part of a greater project whose primary objective is the analysis and characterization of the raw materials used for the construction of architectural elements and artifacts made out of ophiolitic rocks, and more precisely serpentinite, during the Minoan period. In parallel, through the examination of specimens from all the serpentinite outcrops of Crete and the comparison of the analytical results with those acquired from the archaeological objects, a better understanding of the trade networks throughout the Minoan period will be gained. Despite the fact that the analysis of the geological specimens is carried out through the application of several physicochemical techniques, the mineralogical characterization of the archaeological objects is achieved through the sole application of non-destructive and non-invasive Raman spectroscopy. Nevertheless, the targeted use of this technique is a common ground for the analysis of both geological specimens and objects of archaeological value. This has made it possible to create an innovative data base consisting of analytical and spatial data from both categories of object. Within the concept of the present work, two examples from the Knossos area are presented: the stone drain from the “House of the High Priest” and the column base located in the “court of the stone spout” in the Palace of Knossos.