In the framework of the research programme “Immured Vessels in Byzantine and Post-Byzantine Churches of Greece”, conducted by the National Hellenic Research Foundation in collaboration with the local Ephorates of Antiquities, churches decorated with immured vessels in their exterior walls, as well as the ceramics themselves, were recorded and documented. The paper presents the preliminary results of the research in Rethymnon Prefecture, conducted by the archaeologists of the Ephorate of Antiquities of Rethymno (former 28th Ephorate of Byzantine Antiquities). To date, 87 churches with immured vessels in their exterior walls have been traced in the region, among them the earliest example on the island of Crete, dating from the 12th century. The paper focuses on the presentation of the monuments, their architectural type, their dispersion in the area and most importantly their chronology – aiming to answer the question whether the study of the vessels could be used as a criterion for dating the containing monument.